Treatment of small melanomas is often not necessary, but large tumors can cause discomfort and are usually surgically removed. Cisplatin and cryotherapy can be used to treat small tumors less than 3 centimeters, but tumors may reoccur.  Cimetidine , a histamine stimulator, can cause tumors to regress in some horses, but may take up to 3 months to produce results and multiple treatments may be needed throughout the horse's life.  There are few viable treatment options for horses with metastatic melanoma. However, gene therapy injections utilizing interleukin-12 and 18-encoding DNA plasmids have shown promise in slowing the progression of tumors in patients with metastatic melanoma. 
Tuberculosis, sarcoidosis, and lupus erythematosus are not causally related. However, occasionally, a patient may develop any two or all three diseases. In your case with such a strong family history of tuberculosis, your doctor should do all appropriate tests to make sure that you do not have tuberculosis. Occasionally, it can be difficult to differentiate between sarcoidosis and tuberculosis, particularly in those patients who come from areas of high tuberculosis prevalence.