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mg/day inhaled via jet nebulizer either once daily or divided into 2 doses. The maximum manufacturer recommended total dose is 1 mg/day. The National Asthma Education and Prevention Program Expert Panel defines low dose therapy for budesonide inhalation suspension as mg/day, medium dose therapy as 1 mg/day, and high dose therapy as 2 mg/day for children ages 5 to 11 years. Titrate to the lowest effective dose once asthma stability is achieved. Prolonged use of high doses, ., 2 mg/day, may be associated with additional adverse effects.

Inhalation Suspension (administer via jet nebulizer):
Age: 1 to 8 years: Initial and maximum dose are based on prior asthma therapy:
-Previously treated with bronchodilators alone: mg via oral inhalation once a day or mg via oral inhalation twice a day; Maximum daily dose: mg
-Previously treated with inhaled corticosteroids: mg once a day or mg twice a day; may increase up to mg twice a day; Maximum daily dose: 1 mg
-Previously treated with oral corticosteroids: 1 mg once a day or mg twice a day; Maximum daily dose: 1 mg

Comment: For symptomatic patients who do not respond to non-steroid therapy, an initial inhalation suspension dose of mg once a day may be considered.

FLEXHALER(R) Inhalation Powder (oral inhaler):
Age: 6 to 12 years:
-Initial dose: 180 mcg via oral inhalation twice a day; some patients may require an initial dose of 360 mcg twice a day
-Maintenance dose: May increase dose after 1 to 2 weeks if response is not adequate; once asthma stability has been achieved, titrate to the lowest effective dose to reduce the possibility of side effects
-Maximum dose: 360 mcg twice a day

TURBUHALER(R) Inhalation Powder (oral inhaler):
Age 6 to 12 years:
-Initial dose: 100 to 200 mcg via oral inhalation twice a day
Maintenance dose: Lowest dose that keeps patient symptom-free

TURBUHALER(R) Inhalation Powder (oral inhaler):
Age: Over 12 years:
Initial dose: 400 to 2400 mcg via oral inhalation daily in divided doses
Maintenance dose: 200 to 400 mcg via oral inhalation twice a day; higher doses may be necessary for longer or shorter periods of time in some patients; after asthma stability has been achieved, titrate to the lowest effective dose to reduce the possibility of side effects
-Once daily dosing may be considered in patients requiring 400 mcg per day; dose should be given in the evening

Comments:
-Improvement in asthma control can occur as early as 24 hours; maximum benefit is usually achieved within 1 to 2 weeks; individual patients may experience a variable onset and degree of symptom relief.
-If asthma symptoms arise between doses, a fast acting inhaled bronchodilator should be used for immediate relief; this drug should not be used for the relief of acute bronchospasm.
-Once daily dosing may be used unless it does not provide adequate control, then dosing should be administered as a divided dose, adjusting dose as needed.
-Once asthma stability has been achieved, titrate to the lowest effective dose to reduce the possibility of side effects.

Use: For the maintenance treatment of asthma as prophylactic therapy.

Budesonide is metabolized via CYP3A4. Potent inhibitors of CYP3A4 can increase the plasma concentrations of budesonide. Co-administration of ketoconazole (inhibitor of CYP3A4) results in an 8-fold increase in AUC of oral budesonide, compared to budesonide alone. Grapefruit juice, an inhibitor of gut mucosal CYP3A, approximately doubles the systemic exposure of oral budesonide. Conversely, induction of CYP3A4 can result in the lowering of budesonide plasma concentrations. The effect of CYP3A4 inhibitors and inducers on the pharmacokinetics of UCERIS rectal foam have not been studied [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS ].

Dosage requirements of corticosteroids vary among individuals and the diseases being treated. In general, the lowest effective dose is used. The oral dose range is 2-60 mg daily depending on the disease. Depo-medrol doses are 10-80 mg injected into muscle every 1-2 weeks, and Solu-medrol doses are 10-250 mg intravenous or intramuscular injections up to 6 times daily. The initial dose should be adjusted based on response. Corticosteroids given in multiple doses throughout the day are more effective but also more toxic than the same total daily dose given once daily, or every other day.

Hi Sheri,
I am so sorry to hear about how this nasty colitis has affected you and the rest of your family so much. I definitely understand exactly what you are talking about. In fact, i am in the middle of a nasty flare up at this very moment, and wanting more than ever to get things back in order to move on through life(its a great feeling writing like this to someone who knows exactly what I’m talking about)j
Anyways, to answer your question as best I can “What is remission exactly..?”
For me, I felt I was in remission finally after just about one year of being diagnosed. After my diagnosis I had tried prednisone,asascol,colazal,sulfasalazine,Remicade, and Humira(in that order) also some enemas mixed in. Anyways, nothing seemed to get me in any type of symptom free state for more than a day or two, so I considered them all a failure in that respect. Once I started the SCD diet after trying all those medications, things started to improve. By improve I mean harder bowel movemnts, blood getting much less in volume and in frequency, and gaining weight back. Eventually after about 6 weeks on the strict diet, I was off all medications and taking 1-2 craps per day. Things were looking really up for the next 14 months. But, now, I find myself in a pretty bad flare up once again. I have not gone on any meds yet, and the bleeding and loose stools are back. I do believe that me changing my strictness on the diet over the last six months very well could be the contributing factor in why I am where I am currently. So I still have faith in the diet, especially as I know far too many people who have had much more continued success on it than me, and who are also more strict on it than I am.

Uceris steroid

uceris steroid

Dosage requirements of corticosteroids vary among individuals and the diseases being treated. In general, the lowest effective dose is used. The oral dose range is 2-60 mg daily depending on the disease. Depo-medrol doses are 10-80 mg injected into muscle every 1-2 weeks, and Solu-medrol doses are 10-250 mg intravenous or intramuscular injections up to 6 times daily. The initial dose should be adjusted based on response. Corticosteroids given in multiple doses throughout the day are more effective but also more toxic than the same total daily dose given once daily, or every other day.

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